Question

Which one of the following microscopes has working principle most similar to the way a blind person reads?

• A. Confocal microscope
• B. Epifluorescence microscope
• C. Atomic force microscope
• D. Total internal reflection fluorescence microscope

Hint:

Atomic Force Microscopes (AFMs) use tactile-like interactions with surfaces, which makes them unique in their ability to provide topographical maps at the atomic level.

Answer 1

The Correct Option is C

Step 1: Understanding the working principle of the Atomic Force Microscope (AFM).
The Atomic Force Microscope (AFM) works by scanning a sharp tip over a surface, measuring the interactions between the tip and the surface. This method can be compared to the way a blind person reads Braille, as both methods involve tactile feedback through surface interactions.

Step 2: Analyzing the options.
(A)Confocal microscope: This type of microscope uses focused light and does not operate based on tactile interaction, so it is not similar to how a blind person reads.
(B)Epifluorescence microscope: Similar to confocal microscopes, these involve light detection and not tactile feedback.
(C)Atomic force microscope: Correct — The AFM uses a sharp tip to scan a surface, much like a blind person reads by feeling raised dots, making it the most similar.
(D)Total internal reflection fluorescence microscope: This microscope involves light and fluorescence, which does not align with tactile feedback.

Step 3: Conclusion.
The correct answer is (C)Atomic force microscope, as its working principle most closely resembles the way a blind person reads using Braille.