Question

Which one of following is functions of PGI2?

• A. Inhibits platelet aggregation
• B. Is a vasodilator
• C. Is pyrogenic like PGE2
• D. All of the above

Answer 1

The Correct Option is D

Prostaglandin I2 (PGI2), also known as prostacyclin, plays several important roles in the human body, particularly in the cardiovascular system and inflammatory responses.

• Inhibits platelet aggregation: PGI2 acts as an antiplatelet agent. It inhibits the aggregation of platelets, which is crucial in preventing unnecessary blood clot formation within the vessels.
• Is a vasodilator: PGI2 causes dilation of the blood vessels, leading to a decrease in blood pressure and improvement in blood flow. This function is essential for maintaining adequate blood circulation.
• Is pyrogenic like PGE2: Like prostaglandin E2 (PGE2), PGI2 has a role in producing fever during inflammatory and immune responses by acting on the hypothalamus.

Combining these roles, PGI2 effectively supports vital physiological processes by regulating vascular tone, preventing thrombosis, and participating in inflammatory reactions. Therefore, the correct option is All of the above, encompassing its comprehensive functions.