Question

Which of the following phenothiazine neuroleptic is a piperidine derivative?

• A. Thioridazine
• B. Trifluperazine
• C. Perphenazine
• D. Promazine

Hint:

When studying neuroleptics, remember that piperidine derivatives are a sub-class of phenothiazines and are used in treating psychotic disorders.

Answer 1

The Correct Option is A

Step 1: Understanding the types of neuroleptics.
Neuroleptics, also known as antipsychotic drugs, are classified based on their chemical structure. The phenothiazines are a class of antipsychotics that contain a phenothiazine nucleus. They are further divided into three categories: aliphatic, piperazine, and piperidine derivatives.
Step 2: Identifying the piperidine derivative.
- (A) Thioridazine: Thioridazine is a phenothiazine neuroleptic that is a piperidine derivative.
- (B) Trifluperazine: Trifluperazine is a piperazine derivative, not a piperidine derivative.
- (C) Perphenazine: Perphenazine is a piperazine derivative, not a piperidine derivative.
- (D) Promazine: Promazine is an aliphatic derivative, not a piperidine derivative.

Step 3: Conclusion.
Thus, the correct answer is (A) Thioridazine, as it is the only piperidine derivative among the options. Final Answer:} (A) Thioridazine.