Question:

Which of the following molecules is not having glycosidic linkage?

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In biochemistry, understanding the structure and bonding of carbohydrates is crucial for applications in food science, nutrition, and bioengineering.
Updated On: May 14, 2025
  • Sucrose
  • Glucose
  • Maltose
  • Cellulose
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The Correct Option is B

Approach Solution - 1

Step 1: Define glycosidic linkage. A glycosidic linkage is a type of covalent bond that joins a carbohydrate molecule to another group, which can be another carbohydrate. It is formed by a dehydration reaction between two monosaccharides. 
Step 2: Analyze each molecule. Sucrose (table sugar) is a disaccharide consisting of glucose and fructose linked via a glycosidic bond.
Glucose is a simple sugar or monosaccharide, lacking glycosidic linkages as it does not bond with another sugar in its basic form.
Maltose is a disaccharide composed of two glucose units linked by a glycosidic bond.
Cellulose is a polysaccharide made up of multiple glucose units linked by glycosidic bonds, forming the structural component of plant cell walls. Conclusion: Glucose, being a monosaccharide, does not have glycosidic linkages, making it the correct answer.

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Approach Solution -2

To solve the problem, we need to determine which of the following molecules does not have a glycosidic linkage.

1. Understanding Glycosidic Linkages:
A glycosidic linkage is a covalent bond that forms between two monosaccharide molecules, such as in disaccharides, oligosaccharides, and polysaccharides. This bond is formed when a hydroxyl group (-OH) of one monosaccharide reacts with the anomeric carbon of another monosaccharide, releasing a molecule of water.

2. Analyzing the Options:
Let's examine the molecules:

  • Sucrose: Sucrose is a disaccharide composed of glucose and fructose linked by a glycosidic bond, so it contains a glycosidic linkage.
  • Glucose: Glucose is a monosaccharide and does not contain a glycosidic linkage by itself. Glycosidic linkages form only when glucose molecules join with others to form disaccharides or polysaccharides.
  • Maltose: Maltose is a disaccharide composed of two glucose units connected by a glycosidic bond, so it contains a glycosidic linkage.
  • Cellulose: Cellulose is a polysaccharide made up of glucose molecules joined by glycosidic linkages, so it contains glycosidic linkages.

3. Conclusion:
Glucose is the only molecule listed that does not contain a glycosidic linkage, as it is a monosaccharide.

Final Answer:
The correct answer is (B) Glucose.

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