Which of the following Marker is increased in patient with Ovarian Cancer?
Show Hint
- CA 15 - 3
- CA - 125
- CA 19 - 9
- Protein S100 B
The Correct Option is B
Solution and Explanation
Tumor markers are measurable substances, usually proteins, present in blood, urine, or tissues that indicate the presence of certain cancers.
Step 2: Ovarian cancer and CA-125.
CA-125 is a glycoprotein antigen that is elevated in about 80% of women with epithelial ovarian cancer.
It is not only used for diagnosis but also for monitoring recurrence and response to treatment.
Step 3: Analysis of options.
- (A) CA 15-3: Typically elevated in breast cancer, not ovarian cancer.
- (B) CA-125: Correct, strongly linked with ovarian cancer.
- (C) CA 19-9: Elevated in gastrointestinal and pancreatic cancers.
- (D) Protein S100 B: Associated with melanoma and nervous system tumors.
Step 4: Conclusion.
The marker increased in ovarian cancer patients is CA-125.
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