Question:

Which of the following is true of protein synthesis ONLY in prokaryotes?

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Prokaryotes can translate mRNA even before transcription completes — a key distinguishing feature.
Updated On: Dec 14, 2025
  • Translation and transcription are coupled
  • The codon AUG codes for the start signal
  • The tRNA anticodon can bind to two or more different codons
  • The functional ribosomes contain two subunits constructed of proteins and RNA
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The Correct Option is A

Solution and Explanation

Step 1: Understand prokaryotic gene expression.
In prokaryotes, the absence of a nucleus allows transcription and translation to occur simultaneously in the cytoplasm. This coupling is unique to prokaryotes.
Step 2: Analyze the options.
(A) Correct — transcription-translation coupling is exclusive to prokaryotes.
(B) Incorrect — AUG is a start codon in both prokaryotes and eukaryotes.
(C) Incorrect — wobble base pairing occurs in both groups.
(D) Incorrect — both prokaryotic and eukaryotic ribosomes have two subunits made of rRNA and proteins.
Step 3: Conclusion.
Thus, only option (A) is exclusively true for prokaryotic protein synthesis.
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