Question:

Which of the following is the earliest rising cardiac biomarker after myocardial infarction?

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Remember the timeline: Myoglobin earliest (but low specificity), followed by CK-MB, then troponins (gold standard for specificity).
Updated On: Dec 26, 2025
  • CK-MB
  • Troponin I
  • Myoglobin
  • LDH
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The Correct Option is C

Solution and Explanation

Step 1: Understanding the question.
The question asks for the cardiac biomarker that rises earliest after myocardial infarction, typically within the first few hours.
Step 2: Analyzing the options.
(A) CK-MB: Rises after 4-6 hours.
(B) Troponin I: Highly specific but rises after 3-6 hours.
(C) Myoglobin: Correct — It is the earliest marker, rising within 1-3 hours due to its small size and rapid release from damaged myocardium.
(D) LDH: Rises much later, after 24 hours.
Step 3: Conclusion.
The correct answer is (C) Myoglobin, as it is the earliest rising biomarker after myocardial infarction.
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