Question

Which of the following is not a sequence alignment tool

• A. BLAST
• B. FASTA
• C. CLUSTAL
• D. ROSMAL

Hint:

• Common Sequence Alignment Tools:
  • Pairwise Local Alignment BLAST, FASTA, Smith-Waterman algorithm implementations.
  • Pairwise Global Alignment Needleman-Wunsch algorithm implementations.
  • Multiple Sequence Alignment CLUSTAL (ClustalW, Clustal Omega), MUSCLE, MAFFT, T-Coffee.
• Always check for commonly known tools first when asked to identify one that doesn't belong.

Answer 1

The Correct Option is D

In biotechnology, several tools are used for sequence alignment, which is a method of arranging the sequences of DNA, RNA, or protein to identify regions of similarity.

• BLAST (Basic Local Alignment Search Tool): A widely used tool for comparing an input sequence against a database and identifying regions of similarity.
• FASTA: Another algorithm for sequence alignment, known for its speed and sensitivity in searching for similarities.
• CLUSTAL: Primarily used for multiple sequence alignments, allowing the comparison of three or more biological sequences.
• ROSMAL: This is not recognized as a sequence alignment tool. It differs from the other tools listed, which are established methods for performing sequence alignment.

Therefore, the option ROSMAL is not a sequence alignment tool.