Question

Which of the following is a method to conduct phylogeny of protein and DNA sequences?

• A. BLAST
• B. OMNIBUS
• C. Maximum likelihood
• D. DAVID

Hint:

In phylogenetic analysis, the Maximum Likelihood method is a powerful statistical approach for inferring evolutionary trees. It estimates the tree structure that maximizes the likelihood of observing the given sequence data.

Answer 1

The Correct Option is C

Step 1: Understanding Phylogeny.
Phylogeny refers to the evolutionary history of species or genes. It often involves constructing phylogenetic trees that depict evolutionary relationships based on genetic data (such as protein or DNA sequences). Step 2: Maximum Likelihood Method.
The Maximum likelihood method is a statistical approach used for constructing phylogenetic trees. It calculates the probability of obtaining observed data given a specific tree structure. It is one of the most commonly used methods in phylogenetic analysis and helps in estimating the evolutionary relationships between species based on sequence data. BLAST is a tool used for sequence alignment, but it is not a method for conducting phylogeny itself.
OMNIBUS is a tool for multi-omics data analysis, but it is not specifically for phylogenetic analysis.
DAVID is used for functional annotation and gene list enrichment, not for phylogenetic analysis.
Step 3: Conclusion.
The correct answer is Maximum likelihood, as it is a widely used method for inferring phylogenetic trees and evolutionary relationships based on protein and DNA sequence data.