Statins are a class of lipid-lowering medications that reduce illness and mortality in those who are at high risk of cardiovascular disease. They function by inhibiting the enzyme \textit{HMG-CoA reductase}, which plays a central role in the production of cholesterol in the liver. By reducing the synthesis of cholesterol, statins help lower LDL (low-density lipoprotein) cholesterol, commonly known as "bad" cholesterol, which is a major risk factor for atherosclerosis and heart disease.
Option (a) Beta-blockers are used to manage blood pressure and heart rate but do not directly affect cholesterol levels.
Option (c) Antacids neutralize stomach acid and are used in conditions like acid reflux—not cholesterol-related.
Option (d) Antihistamines are used to treat allergic reactions and have no role in cholesterol regulation.
Hence, the correct and most appropriate option is (b) Statins.