Question:

Which of the following does not involve in Friedel-Crafts reaction?

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Aromatic amines do not undergo Friedel-Crafts due to catalyst complexation with –NH$_2$.
Updated On: Jun 4, 2025
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The Correct Option is B

Solution and Explanation

Aniline (–NH$_2$) is a strong electron-donating group but forms a complex with AlCl$_3$ catalyst, deactivating the ring for Friedel-Crafts reactions.
Other compounds (benzene, anisole, chlorobenzene) can participate.
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