Question:

Which of the following correctly represents hydrogen bonded pairs in DNA?

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Base Pairing in DNA.
  • G $\equiv$ C: Three hydrogen bonds.
  • T = A: Two hydrogen bonds.
  • This ensures specificity and stability in the double-stranded DNA structure.
Updated On: May 20, 2025
  • $G = C$ ; $T \equiv A$
  • $G \equiv T$ ; $A = C$
  • $G = A$ ; $T \equiv C$
  • $G \equiv C$ ; $T = A$
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The Correct Option is D

Approach Solution - 1

DNA consists of two complementary strands held together by hydrogen bonds between nitrogenous bases:
  • Guanine (G) forms three hydrogen bonds with Cytosine (C) → represented as G $\equiv$ C.
  • Thymine (T) forms two hydrogen bonds with Adenine (A) → represented as T = A.
This specific and complementary pairing ensures the double helix structure of DNA is stable.
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Approach Solution -2

Step 1: Understand hydrogen bonding in DNA base pairs
DNA structure is stabilized by hydrogen bonds between complementary nitrogenous bases. These base pairs follow Chargaff's rules and specific hydrogen bonding patterns.

Step 2: Hydrogen bonding between Guanine (G) and Cytosine (C)
Guanine pairs with Cytosine via three hydrogen bonds, which is represented as $G \equiv C$. This triple bond makes the G-C pair stronger and more stable.

Step 3: Hydrogen bonding between Thymine (T) and Adenine (A)
Thymine pairs with Adenine through two hydrogen bonds, represented as $T = A$. This double bond is slightly weaker than the G-C pairing.

Step 4: Conclusion
Therefore, the correct representation of hydrogen bonded pairs in DNA is $G \equiv C$ and $T = A$, reflecting the triple and double hydrogen bonds respectively.
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