Question

Which of the following condition is NOT caused by Parvovirus B₁₉ ?

• A. Roseola infantum
• B. Aplastic anemia in sickle cell disease
• C. Fetal hydrops
• D. Erythema infectiosum

Answer 1

The Correct Option is A

Parvovirus B₁₉ is a virus known to cause several specific conditions. It primarily affects red blood cell production, which leads to various clinical manifestations. Let's explore the conditions caused by Parvovirus B₁₉ and identify which condition from the options is not caused by this virus.

• Aplastic anemia in sickle cell disease: Parvovirus B₁₉ can lead to an aplastic crisis in patients with sickle cell disease. This occurs because the virus infects erythroid progenitor cells in the bone marrow, resulting in the cessation of red blood cell production, which is crucial for individuals with pre-existing hemolytic disorders.
• Fetal hydrops: During pregnancy, Parvovirus B₁₉ infection can cross the placenta and cause severe anemia in the fetus, potentially leading to non-immune fetal hydrops, a condition characterized by fluid accumulation in fetal compartments.
• Erythema infectiosum: Also known as "fifth disease," this condition is a classic manifestation of Parvovirus B₁₉ and presents with a characteristic "slapped cheek" rash in children.
• Roseola infantum: This condition, which presents with a sudden high fever followed by a rash as the fever subsides, is typically caused by Human Herpesvirus 6 (HHV-6) or sometimes HHV-7, not by Parvovirus B₁₉.

Given this information, the condition not caused by Parvovirus B₁₉ is Roseola infantum.