Question:

Which is the “Only enzyme” that has “Capability” to catalyse Initiation, Elongation and Termination in the process of transcription in prokaryotes

Updated On: Nov 13, 2025
  • DNase

  • DNA dependent DNA polymerase

  • DNA dependent RNA polymerase

  • DNA Ligase

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The Correct Option is C

Solution and Explanation

The question asks for the enzyme that is capable of catalyzing the initiation, elongation, and termination phases in the transcription process in prokaryotes. Let's analyze each option to identify the correct answer:

  1. DNase : DNase refers to deoxyribonuclease, an enzyme that digests or breaks down DNA molecules. It does not have any role in the transcription process, which involves RNA synthesis.
  2. DNA dependent DNA polymerase : This enzyme is involved in DNA replication, where it synthesizes a new DNA strand complementary to the template strand. It is not involved in transcription, which is the synthesis of RNA.
  3. DNA dependent RNA polymerase : This is the enzyme responsible for transcription in prokaryotes. It binds to the DNA and synthesizes RNA by following the sequence of the DNA template. It can initiate the synthesis, elongate the RNA strand, and terminate the transcription once the entire gene has been transcribed. Hence, this enzyme catalyzes initiation, elongation, and termination of transcription and is the correct answer.
  4. DNA Ligase : DNA ligase is an enzyme that connects DNA strands together by forming phosphodiester bonds. It primarily functions in DNA replication and repair, not in transcription.

Thus, the only enzyme capable of catalyzing initiation, elongation, and termination in prokaryotic transcription is the DNA dependent RNA polymerase.

Conclusion: The correct answer is DNA dependent RNA polymerase, as it carries out all critical steps in transcription of prokaryotes.

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Concepts Used:

Discovery of DNA

DNA - Discovery

Many individuals believe that American biologist - "James Watson" and English physicist - “Francis Crick” discovered DNA in the 1950s. Actually, this is not the case. Preferably, DNA was first recognized in the late 1860s by Swiss chemist - “Friedrich Miescher”.

Read More: Structure of DNA

What actually DNA is?

DNA is self-replicating material that exists in every living organism. In easiest terms, it is a carrier of all genetic information. It contains the instructions required for organisms to develop, grow, survive, and reproduce. It’s one of the longest molecules that contain our genetic “code,” or recipe. This recipe is the initial point for our development, but DNA’s interaction with outside impacts such as our lifestyle, environment, and nutrition ultimately forms human beings.

DNA is a composition of molecules known as nucleotides. Each nucleotide comprises a sugar and phosphate group, also nitrogen bases. These nitrogen bases are further tumbledown into four types, including:

  • Adenine (A)
  • Cytosine (C)
  • Guanine (G)
  • Thymine (T)