Question:

Which is the most common pancreatic endocrine neoplasm ?

Updated On: Jul 15, 2025
  • Insulinoma
  • Gastrinoma
  • VI Poma
  • Glucagonoma
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The Correct Option is A

Solution and Explanation

The most common pancreatic endocrine neoplasm is Insulinoma. Insulinomas are tumors that originate from the beta cells in the pancreas, which are responsible for insulin secretion. This type of tumor is characterized by excess production of insulin, leading to hypoglycemia. Let's understand why Insulinomas are considered the most common:

  • Incidence: Insulinomas have the highest occurrence rate among pancreatic endocrine tumors. They account for a significant proportion of cases compared to other types of pancreatic endocrine neoplasms.
  • Symptoms: The characteristic symptom of an insulinoma is hypoglycemia. Patients often experience symptoms such as confusion, sweating, weakness, and even unconsciousness due to low blood sugar levels.
  • Diagnosis: Insulinomas are typically diagnosed through a combination of fasting blood tests showing low glucose levels alongside high insulin levels, imaging studies, and sometimes surgical exploration.

Other pancreatic endocrine tumors like gastinomas, VIPomas, and glucagonomas occur less frequently. Thus, Insulinoma stands as the most prevalent pancreatic endocrine neoplasm.

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