Question

Which is the best investigation for carcinoma head of pancreas:

• A. Guided biopsy
• B. ERCP
• C. Transduodenal/transperitoneal sampling
• D. EUS

Answer 1

The Correct Option is D

To determine the best investigation for carcinoma of the head of the pancreas, it is crucial to use a method that provides detailed images and allows for tissue sampling if needed. The investigation options available are:

• Guided biopsy
• ERCP (Endoscopic Retrograde Cholangiopancreatography)
• Transduodenal/transperitoneal sampling
• EUS (Endoscopic Ultrasound)

Among these options, Endoscopic Ultrasound (EUS) stands out as the preferred investigation. Here's why:

• Precision and Detail: EUS is highly effective in providing detailed images of the pancreas and nearby structures. It uses high-frequency sound waves, giving it superior resolution compared to other imaging techniques.
• Biopsy Capability: EUS can be combined with fine needle aspiration (FNA) to obtain tissue samples. This feature is crucial for the accurate diagnosis and staging of pancreatic cancer.
• Minimally Invasive: EUS is less invasive compared to transduodenal or transperitoneal approaches, reducing patient discomfort and recovery time.
• No Radiation: As EUS uses ultrasound for imaging, there is no exposure to radiation, making it safer for patients.

Therefore, EUS is considered the best investigation for diagnosing carcinoma of the head of the pancreas due to its accuracy, ability to provide tissue samples, and overall patient safety.