Question

Which is not true for karyotyping?

• A. Used to determine chromosome number
• B. Used to determine chromosome size
• C. Used in DNA amplification
• D. Used to detect diseases

Hint:

Karyotyping is used to analyze chromosomes, not for DNA amplification, which is done by PCR.

Answer 1

The Correct Option is C

Step 1: Understanding Karyotyping 
Karyotyping is used to examine the number, shape, and size of chromosomes in a cell, helping detect genetic diseases. 
Step 2: Evaluating the Options 
- Used to determine chromosome number: True, karyotyping is used to count chromosomes. 
- Used to determine chromosome size: True, karyotyping helps assess the size of chromosomes. 
- Used in DNA amplification: Incorrect, DNA amplification is done through PCR, not karyotyping. 
- Used to detect diseases: True, karyotyping helps detect chromosomal abnormalities linked to diseases. 
Step 3: Conclusion 
Karyotyping does not involve DNA amplification, making option (C) the correct answer.