Question:

Which enzyme is involved in the base excision repair of DNA?

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DNA glycosylase removes damaged bases, initiating the base excision repair process.
Updated On: Feb 10, 2025
  • Purine glycosylase
  • P1 nuclease
  • Endonuclease II
  • DNA glycosylase
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The Correct Option is D

Solution and Explanation

Step 1: Understanding Base Excision Repair 
Base excision repair is a DNA repair mechanism that removes damaged bases and replaces them with the correct ones. 
Step 2: Role of DNA Glycosylase 
- DNA glycosylase: The enzyme responsible for removing damaged bases in base excision repair. 
- Other enzymes like Purine glycosylase, P1 nuclease, and Endonuclease II are involved in different repair mechanisms. 
Step 3: Conclusion 
DNA glycosylase is the enzyme responsible for initiating base excision repair.

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