Question

Which among the following will the choice of antibiotic for a bedridden patient with catheter-related UTI and pneumonia.

• A. Amoxicillin
• B. Beta Lactam antibiotics with beta lactamase
• C. 3rd gen cephalosporins
• D. 2nd gen cephalosporins

Answer 1

The Correct Option is B

A patient with catheter-related urinary tract infection (UTI) and pneumonia requires careful consideration for antibiotic selection to effectively treat both conditions. Catheter-related UTIs are often caused by Gram-negative bacteria and may involve organisms resistant to standard antibiotics due to the healthcare setting exposure. Pneumonia in bedridden patients might be hospital-acquired, making it resistant to first-line antibiotics.

To address infections potentially caused by resistant strains, antibiotics that combine a beta-lactam core with beta-lactamase inhibitors are recommended:

• Beta-Lactam Antibiotics with Beta-Lactamase Inhibitors: These combinations inhibit the bacterial enzymes that confer resistance to many beta-lactam antibiotics, making them suitable for infections like catheter-related UTIs and pneumonia in hospitalized or bedridden patients.

Other options are less suitable:

• Amoxicillin: While effective against some infections, it's not ideal here due to likely resistance.
• 3rd Gen Cephalosporins: Though effective, they lack a beta-lactamase inhibitor, reducing efficacy against resistant strains.
• 2nd Gen Cephalosporins: Generally less effective against resistant hospital-acquired infections than later generations.