Question:
What will be change observed in liquid chromatography with increased mobile phase flow rate?
What will be change observed in liquid chromatography with increased mobile phase flow rate?
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Higher flow rate = faster elution = shorter retention time (but potentially lower resolution).
Updated On: Jun 16, 2025
- Decreased pressure
- Increased resolution
- Increased sensitivity
- Reduced retention times
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The Correct Option is D
Solution and Explanation
When the mobile phase flow rate increases in liquid chromatography, analytes move through the column more quickly. This leads to reduced retention times, although it may compromise resolution and sensitivity.
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