Question

What is the average molecular weight of Type I collagen molecule?

• A. 300 KDa
• B. 3000 KDa
• C. 30 KDa
• D. 3 KDa

Hint:

The high molecular weight of Type I collagen (around 3000 KDa) is a key feature that supports its role in providing strength and structure to connective tissues.

Answer 1

The Correct Option is B

Type I collagen is one of the largest and most important proteins in the body, playing a key role in the structural integrity of connective tissues. Due to its triple-helical structure composed of three long polypeptide chains, Type I collagen has a large molecular weight, typically around 3000 KDa (kilodaltons). This large size is essential for collagen's function in providing tensile strength and support to tissues such as bones, tendons, and skin. The large molecular weight is a direct result of the long amino acid sequences in each of the three polypeptide chains that make up the collagen molecule. This extensive molecular structure contributes to collagen's ability to resist mechanical stress and form strong connective tissues. While collagen molecules are large, they are also fibrous and can aggregate into even larger structures known as collagen fibers, which contribute to the mechanical properties of tissues.