Question

What is the advantage of fixed dose combination of drugs

• A. Increases efficacy of drug
• B. Decreases adverse effects
• C. Patient compliance improved
• D. All of the above

Answer 1

The Correct Option is D

Fixed dose combinations (FDCs) of drugs offer several advantages which can address multiple aspects of pharmacological treatments:

1. Increases efficacy of drug: Combining drugs with complementary mechanisms of action can enhance the therapeutic effectiveness of the treatment, providing a broader spectrum of action or targeting different pathways within a disease process. This synergy can lead to improved clinical outcomes.
2. Decreases adverse effects: By optimizing dosages in a fixed combination, it is often possible to reduce the side effects associated with each individual drug. Each component may be used at a lower dose than if it were administered alone, potentially minimizing dose-dependent adverse effects.
3. Improved patient compliance: FDCs simplify pharmacotherapy by reducing the number of pills a patient needs to take, which can significantly enhance adherence to the medication regimen. This is particularly beneficial in chronic conditions where multiple medications are required.
4. All of the above: The combined effects of increased efficacy, decreased adverse effects, and improved compliance contribute to the overall advantage of using FDCs in medical treatment strategies.

Thus, the correct answer is: All of the above, as it encapsulates the comprehensive benefits of using fixed dose combinations of drugs in therapy.