Question:

Transgenic and knock out animal's means

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  • Transgenic Contains an added foreign gene (transgene).
  • Knockout Has a specific endogenous gene inactivated/deleted.
  • Knock-in An endogenous gene is replaced with a modified version or another gene is inserted at a specific locus.
  • An animal can be engineered to be both transgenic (for one gene) and a knockout (for another gene).
Updated On: Jun 12, 2025
  • Gene knocked out and new gene added animals
  • Gene knocked out but no new gene added animals
  • Gene not removed but new gene added animals
  • New Gene added and existing gene knocked out animals
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The Correct Option is A

Solution and Explanation

Transgenic and Knockout Animals: Explanation and Relevance

In biotechnology, transgenic animals are those that have had a new gene added to their genome using recombinant DNA technology. This process involves introducing a foreign gene to impart new traits or characteristics beneficial for research, agriculture, or medicine.

Knockout animals, on the other hand, have had one or more of their own genes entirely deactivated or "knocked out." This is done to study the function of a particular gene by observing the effects of its absence.

Understanding these concepts, the correct term 'Transgenic and Knockout Animals' can be defined as animals that:

  • Gene knocked out: A specific gene in the animal's genome is deactivated or removed.
  • New gene added: A new or foreign gene is inserted into the animal's genome to introduce novel traits or characteristics.

Hence, transgenic and knockout animals involve both the removal or inactivation of an existing gene and the addition of a new gene.

The correct option is: Gene knocked out and new gene added animals

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