Tranquilizers are central nervous system depressants that bring about a calming effect and induce mild sedative effects. Most of these drugs are derivatives of Barbituric acid-like Veronal, Mytal, Nembutal, Luminal, Seconal.
Specifically, to reduce states of anxiety and stress.
Mode of action- Acts on the central nervous system by blocking the neurotransmitter dopamine in the brain.
Tranquillizers come in two varieties:
Minor Tranquillizers also called anxiolytics are used for sedation and to treat anxiety. Today these drugs are called antianxiety medications. The major tranquilizers include:
Ex: Diazepam, Chlordiazepoxide, Lorazepam, Nitrazepam
Ex: Meprobamate
Ex: Hydroxy Lithium Carbonate
Major Tranquillizers also called neuroleptics were developed to treat psychiatric disorders including schizophrenia. These drugs combat hallucinations and other delusions. Usually prescribed for long terms, major Tranquillizers include phenothiazines, thioxanthenes, butyrophenones, clozapine and rauwolfia alkaloids. The major tranquilizers include:
Ex: Chlorpromazine, Prochlorperazine, Trifluoperazine, Thiothiazine
Ex: Haloperidol, Trifluperidol
Ex: Reserpine
Ex: Clozapine
Ex: Thioxanthenes