Question

This vaccine is a toxoid.

• A. Salk's polio vaccine
• B. Vaccine for tetanus
• C. Vaccine for rubella
• D. Vaccine for typhoid

Hint:

Vaccines can be classified into several types based on their composition: \begin{itemize} \item \textbf{Live-attenuated vaccines:} Contain a weakened form of the pathogen (e.g., MMR, chickenpox, oral polio). \item \textbf{Inactivated vaccines:} Contain a killed version of the pathogen (e.g., Salk polio, Hepatitis A, most flu shots). \item \textbf{Toxoid vaccines:} Use inactivated toxins produced by bacteria (e.g., Diphtheria, Tetanus). \item \textbf{Subunit, recombinant, polysaccharide, and conjugate vaccines:} Use specific pieces of the pathogen (e.g., Hepatitis B, HPV, Pneumococcal). \end{itemize} Understanding these classifications helps in identifying the type of vaccine.

Answer 1

The Correct Option is B

Step 1: Understand what a toxoid vaccine is

A toxoid vaccine is a type of vaccine that uses a toxoid, which is an inactivated bacterial toxin. The toxin is chemically treated or heated to destroy its toxic properties while retaining its ability to stimulate an immune response. This immune response protects against the disease caused by the toxin, rather than the bacteria itself.

Step 2: Evaluate each option to identify which is a toxoid vaccine

• Salk’s polio vaccine: An inactivated (killed) vaccine made from poliovirus that has been inactivated with formalin. Not a toxoid vaccine.
• Vaccine for tetanus: Contains inactivated tetanus toxin (tetanus toxoid) which stimulates immunity against the toxin. This is a toxoid vaccine.
• Vaccine for rubella: A live, attenuated viral vaccine containing weakened rubella virus. Not a toxoid vaccine.
• Vaccine for typhoid: Includes various forms like inactivated whole-cell, live attenuated, and capsular polysaccharide vaccines. Since Salmonella typhi does not produce a primary exotoxin, no toxoid vaccine exists for typhoid. Not a toxoid vaccine.

Step 3: Conclude the correct option

Based on the evaluation, only the vaccine for tetanus is a toxoid vaccine.
The final answer is: Vaccine for tetanus.