To determine when the lines are perpendicular, we need to find the dot product of their direction vectors and set it equal to zero.
For the first line: Direction vector \( \vec{d_1} = \langle -3, -4, 3 \rangle \).
For the second line: Direction vector \( \vec{d_2} = \langle -3, 3, -\lambda \rangle \).
The dot product of \( \vec{d_1} \) and \( \vec{d_2} \) is given by:
\[ \vec{d_1} \cdot \vec{d_2} = (-3)(-3) + (-4)(3) + (3)(-\lambda) \]
Simplifying:
\[ \vec{d_1} \cdot \vec{d_2} = 6 - 12 - 3\lambda \]
For the lines to be perpendicular, we require:
\[ 6 - 12 - 3\lambda = 0 \]
Simplifying further:
\[ -6 - 3\lambda = 0 \implies -3\lambda = 6 \implies \lambda = -2 \]
Therefore, the value of \( \lambda \) that makes the lines perpendicular is:
\[ \boxed{\lambda = -2} \]