Question:

The structure of Gly-Ala (Glycylalanine) is:

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Key points about dipeptides: 1. Always drawn with N-terminus (NH$_2$) on left
2. Peptide bonds are rigid and planar
3. R-groups alternate above/below the peptide chain
4. Named from N-terminal to C-terminal residue
Updated On: May 27, 2025
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The Correct Option is B

Approach Solution - 1

Gly-Ala (Glycylalanine) is a dipeptide composed of: - Glycine (Gly) as the N-terminal amino acid.
- Alanine (Ala) as the C-terminal amino acid. Correct structural features: - Free amino group (-NH$_2$) at the N-terminus.
- Free carboxyl group (-COOH) at the C-terminus.
- Peptide bond (-CO-NH-) linking the two amino acids.
- Methyl side chain (-CH$_3$) from alanine. Analysis of options: - Option 1: Shows two separate amino acids (Gly + Ala), not a dipeptide.
- Option 2: Correct dipeptide structure with proper peptide bond.
- Option 3: Incorrect hydroxyl group (OH) at N-terminus.
- Option 4: Shows ester linkage (-CO-O-) instead of peptide bond. 
Thus, the correct answer is (2).

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Approach Solution -2

Glycylalanine is a dipeptide formed from two amino acids:

  • Glycine (Gly): NH2–CH2–COOH
  • Alanine (Ala): NH2–CH(CH3)–COOH

When these two amino acids undergo a condensation reaction, the carboxyl group of glycine reacts with the amino group of alanine, releasing a water molecule and forming a peptide bond (–CO–NH–). 

Resulting Dipeptide Structure (Gly-Ala):
H2N–CH2–CO–NH–CH(CH3)–COOH
The image shown above correctly represents the structure of Glycylalanine, featuring:

  • A terminal amino group from glycine (left side)
  • A peptide linkage between glycine and alanine
  • A terminal carboxylic acid group from alanine (right side)


Final Answer:
The given structure is Gly-Ala (Glycylalanine)

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