Question:

The number of codons effective in coding twenty amino acids:

Updated On: Apr 1, 2025
  • 20
  • 61
  • 32
  • 64
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The Correct Option is B

Approach Solution - 1

The genetic code is the set of rules by which the nucleotide sequence of DNA or RNA is translated into the amino acid sequence of a protein. Codons, which consist of three nucleotides, are the units that encode specific amino acids or stop signals in the genetic code.

There are 20 standard amino acids commonly found in proteins. However, the total number of possible codons is 64(43), which is greater than the number of amino acids. This means that some amino acids are encoded by more than one codon. In fact, 61 out of the 64 codons code for specific amino acids, while the remaining three codons (UAA, UAG, and UGA) serve as stop signals or "termination" codons, indicating the end of protein synthesis.

Therefore, the correct answer is 61, as there are 61 codons that effectively code for the twenty amino acids.

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Approach Solution -2

The genetic code is the set of rules used by living cells to translate information encoded within genetic material (DNA or RNA sequences) into proteins. Each codon, a sequence of three nucleotides, specifies a particular amino acid to be added to the growing polypeptide chain during protein synthesis. 

There are a total of 64 possible codons. However, not all of these codons code for amino acids. Three of them are stop codons. The number of codons that effectively code for the twenty common amino acids is therefore:

61

The remaining three codons (UAA, UAG, and UGA) are stop codons, signaling the termination of protein synthesis. This redundancy in the genetic code (more than one codon per amino acid) is known as codon degeneracy.

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