To find the number of 8-digit odd numbers, consider the following:
- The first digit must be any digit from 1 to 9 (9 options).
- The last digit must be an odd number, i.e., 1, 3, 5, 7, or 9 (5 options).
- The remaining 6 digits can be any digit from 0 to 9 (10 options each).
Thus, the total number of 8-digit odd numbers is:
\[
9 \times 10^6 \times 5 = 45 \times 10^6
\]