The mutation in which a purine is replaced by pyrimidine and vice versa is known as
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Transversion mutations are more disruptive to the DNA sequence than transition mutations due to the structural differences between purines and pyrimidines
A transversion mutation occurs when a purine is substituted by a pyrimidine or a pyrimidine is substituted by a purine This contrasts with transition mutations where purines replace purines or pyrimidines replace pyrimidines
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