Question

By which process miss-incorporated base can change into a permanent mutation?

• A. Replication
• B. Transcription
• C. Translation
• D. Transposition

Hint:

During DNA replication, errors can be introduced that may result in permanent mutations if not corrected by repair mechanisms.

Answer 1

The Correct Option is A

Step 1: Understanding mutation process.
A miss-incorporated base in DNA can cause a permanent mutation if it is replicated and passed on to daughter cells. This occurs during the replication process, where incorrect base pairing is not corrected.
Step 2: Analyzing the options.
(1) Replication: Correct — During DNA replication, if a base is incorrectly incorporated and not repaired, it can lead to a permanent mutation.
(2) Transcription: Incorrect, transcription is the process of synthesizing RNA from DNA, not where permanent mutations occur.
(3) Translation: Incorrect, translation is the process of protein synthesis, not directly related to permanent mutations in DNA.
(4) Transposition: Incorrect, transposition refers to the movement of genetic elements within the genome but doesn't typically result in permanent mutations from miss-incorporated bases.
Step 3: Conclusion.
The process by which a miss-incorporated base becomes a permanent mutation is (1) Replication.