Question:

The method of directly injecting a sperm into ovum is called

Updated On: Apr 10, 2025
  • GIFT
  • ZIFT
  • ICSI
  • IVF-ET
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The Correct Option is C

Approach Solution - 1

Let's analyze the different Assisted Reproductive Technologies (ART) listed: 

  • GIFT (Gamete Intrafallopian Transfer): In this method, both sperm and unfertilized eggs (gametes) are collected and transferred directly into the woman's fallopian tube, where fertilization occurs naturally (in vivo). It does not involve direct injection of sperm into the ovum.
  • ZIFT (Zygote Intrafallopian Transfer): Here, eggs are fertilized with sperm in vitro (outside the body). The resulting zygote(s) are then transferred into the fallopian tube. Fertilization occurs externally, not via direct injection into the ovum.
  • ICSI (Intracytoplasmic Sperm Injection): This is a specialized form of In Vitro Fertilization (IVF) where a single sperm is selected and directly injected into the cytoplasm of an ovum using a micromanipulation technique. This precisely matches the description in the question.
  • IVF-ET (In Vitro Fertilization and Embryo Transfer): This is a broader procedure where fertilization occurs outside the body (in vitro), and the resulting embryo(s) are transferred into the uterus (ET). Standard IVF involves mixing sperm and eggs in a dish, allowing fertilization to happen without direct injection. ICSI is often used as part of an IVF cycle when there are issues with sperm quality or previous fertilization failure, but IVF-ET itself doesn't exclusively mean direct injection.

Therefore, the method of directly injecting a sperm into an ovum is specifically called ICSI (Intracytoplasmic Sperm Injection).

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Approach Solution -2

​The method of directly injecting a sperm into an ovum is known as Intracytoplasmic Sperm Injection (ICSI). This specialized assisted reproductive technology (ART) is primarily utilized to address severe male infertility issues, such as low sperm count or poor sperm motility. During the ICSI procedure, a single sperm is carefully selected and injected directly into the cytoplasm of a mature egg, facilitating fertilization.

ICSI is often employed in conjunction with in vitro fertilization (IVF) when traditional fertilization methods are unlikely to succeed due to sperm-related challenges. By directly introducing the sperm into the egg, ICSI bypasses potential barriers to fertilization, increasing the chances of successful embryo development. ​

The correct answer is (C) : ICSI.

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