Step 1: Standard Equation of the Given Circle
The given circle equation is:
\[
x^2 + y^2 = 10.
\]
This represents a circle centered at \( (0,0) \) with radius \( \sqrt{10} \).
Step 2: Equation of a Tangent to the Circle
The general equation of a tangent to a circle \( x^2 + y^2 = r^2 \) at a point \( (x_1, y_1) \) on the circle is:
\[
x x_1 + y y_1 = r^2.
\]
For our given circle, the equation of the tangent at \( (x_1, y_1) \) is:
\[
x x_1 + y y_1 = 10.
\]
Step 3: Condition for Perpendicular Tangents
If two tangents are perpendicular, their corresponding points of contact satisfy the property:
\[
x_1 x_2 + y_1 y_2 = 0.
\]
Using the combined equation of two perpendicular tangents:
\[
x^2 + y^2 = R^2 + r^2,
\]
where \( R \) is the radius of the locus circle and \( r \) is the radius of the given circle.
Step 4: Finding the Locus Equation
Using \( R^2 = 2r^2 \), we substitute \( r^2 = 10 \):
\[
R^2 = 2(10) = 20.
\]
Thus, the required locus is:
\[
x^2 + y^2 = 20.
\]
Step 5: Conclusion
Thus, the correct answer is \( \mathbf{x^2 + y^2 = 20} \).