The given differential equation is:
\[
(1 + 2e^{-x}) \frac{dy}{dx} - 2e^{-x} y = 1 + e^{-x}
\]
This is a linear first-order differential equation of the form:
\[
\frac{dy}{dx} + P(x) y = Q(x)
\]
To solve it, we need to find the integrating factor. The integrating factor \( \mu(x) \) is given by:
\[
\mu(x) = e^{\int P(x) \, dx}
\]
We need to rewrite the given equation in the standard form:
\[
\frac{dy}{dx} + \left( \frac{-2e^{-x}}{1 + 2e^{-x}} \right) y = \frac{1 + e^{-x}}{1 + 2e^{-x}}
\]
Thus, the integrating factor \( \mu(x) \) is:
\[
\mu(x) = e^{\int \frac{-2e^{-x}}{1 + 2e^{-x}} \, dx}
\]
To simplify this integral, we observe that the factor \( 1 + 2e^{-x} \) makes the expression simpler to integrate, and we find that:
\[
\mu(x) = 1 + 2e^{-x}
\]
Thus, the integrating factor is \( 1 + 2e^{-x} \), which corresponds to option (E).