The improper functioning of 'X' results in Addison's disease. Hormone 'Y' is responsible for the development of secondary female characteristics. 'X' and 'Y' are respectively:
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Match diseases with the gland and function of the hormone. Adrenal cortex — Addison's; Estradiol — female traits.
Addison's disease is caused due to the malfunctioning of the adrenal cortex. Estradiol, a form of estrogen, is responsible for secondary sexual characteristics in females.