Question:

The hormone pepsin is activated by the

Updated On: Aug 1, 2022
  • pH of saliva
  • pH of intestine
  • pH of stomach
  • pH of pancreas.
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The Correct Option is C

Solution and Explanation

The gastric glands of the stomach secrete gastric juice, which contains hydrochloric acid, proenzymes??pepsinogen and prorennin. Hydrochloric acid (HCl) maintains a strongly acidic pH of about 1.5 to 2.5 in the stomach. HCl converts pepsinogen and prorennin into their active forms i.e., pepsin and rennin respectively.
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Concepts Used:

Mechanism of Hormone Action

The mechanism of hormone action is categorised into two classes:

Fixed Membrane Receptor Mechanism-

This type of mechanism is represented by the water-soluble hormones that are amines or proteins in the composition like the growth hormone, oxytocin, ADH, etc. These hormones cannot pass via the lipid membrane. They have their earmark receptor on the cell membrane to which the hormone binds. When the hormone sticks or binds to the specific target receptor, the enzyme adenyl cyclase in the cell membrane is charged. This aids in the production of cyclic AMP. cAMP behaves as the secondary messenger. It diffuses through the cell membrane and activates various enzymatic reactions to cause biochemical changes. The target cell acknowledges these changes and cAMP is deactivated by the enzyme phosphodiesterase.

Mobile Receptor Mechanism-

This type of mechanism is represented by lipid-soluble hormones like fatty acids and steroids that can pass very easily through the plasma membrane. They own intracellular receptors. The hormones stick or bind to the target receptor that activates the enzymatic activity of the cell to bring regard to biochemical changes. Transcription of DNA begins with the hormone-receptor complex. The mRNA is transferred into protein. This protein is the source of biochemical changes inside the cell.