The force between two conducting spheres of same radius having charges +8 μC and -4 μC separated by some distance in air is F. If the spheres are connected by a conducting wire and after some time the wire is removed, then the magnitude of the force between the two conducting spheres is
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Remember that when charges are redistributed, the new force depends on the square of the charges involved.
When the spheres are connected by a conducting wire, the charges redistribute equally. The new charge on each sphere becomes $\frac{+8 \, \mu C + (-4 \, \mu C)}{2} = 2 \, \mu C$. Using Coulomb's law for the force between two charges, the force is proportional to the square of the charge. Hence, the new force will be $8F$.