Question:

The five sentences (labelled 1,2,3,4, and 5) given in this question, when properly sequenced, form a coherent paragraph. Decide on the proper order for the sentence and key in this sequence of five numbers as your answer.
1. Scientists have for the first time managed to edit genes in a human embryo to repair a genetic mutation, fuelling hopes that such procedures may one day be available outside laboratory conditions. 
2.The cardiac disease causes sudden death in otherwise healthy young athletes and affects about one in 500 people overall. 
3. Correcting the mutation in the gene would not only ensure that the child is healthy but also prevents transmission of the mutation to future generations. 
4. It is caused by a mutation in a particular gene and a child will suffer from the condition even if it inherits only one copy of the mutated gene. 
5. In results announced in Nature this week, scientists fixed a mutation that thickens the heart muscle, a condition called hypertrophic cardiomyopathy.

Updated On: Sep 26, 2024
  • 15243
  • 12543
  • 15423
  • 24315
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The Correct Option is A

Solution and Explanation

Statement 1 introduces the paragraph by describing the accomplishment of scientists in editing genes in a human embryo to correct a genetic mutation. Statement 5 follows, explaining how the mutation causing hypertrophic cardiomyopathy was rectified. Statement 2 follows 5, describing the consequences of cardiomyopathy. Statement 4 follows 2, explaining that cardiomyopathy is caused by a mutation in a specific gene, which can cause a child to suffer even if they inherit only one copy of the mutated gene. Finally, statement 3 concludes the paragraph with the reassuring note that correcting the gene mutation allows the child to lead a healthy life and prevents the transmission of the gene to future generations. Therefore, the logical sequence is 15243.

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