Question

The factors favorable for increase of binding affinity of oxygen with haemoglobin

• A. high $pO_{2}$, low $pCO_{2}$, high pH
• B. low $pO_{2}$, high $pCO_{2}$, low pH
• C. high $pO_{2}$, high $pCO_{2}$, low pH
• D. low $pO_{2}$, low $pCO_{2}$, high pH

Hint:

High O\textsubscript{2}, low CO\textsubscript{2}, high pH = stronger O\textsubscript{2} binding to haemoglobin.

Answer 1

The Correct Option is A

Haemoglobin binds oxygen more efficiently under high oxygen pressure $(pO_{2})$, low carbon dioxide pressure $(pCO_{2})$, and alkaline conditions (high pH). These conditions are typically found in the lungs.