Question

The combination of frequency between the genes a and c is 5%; b and c is 15%; b and d is 9%; a and b is 20%; c and d is 24%; and a and d is 29%. Identify the sequence of genes on a linear chromosome:

Hint:

Use recombination frequencies to map genes linearly.
Smallest frequency → closest genes.
Sum of intermediate distances must match total distances.

Answer 1

1. Recombination frequency ∝ distance between genes.
2. Arrange genes to satisfy given distances: a-d = 29%, d-b = 9%, b-c = 15%, a-c = 5%, c-d = 24%, a-b = 20%.
3. The linear sequence satisfying all distances is a, d, b, c.
4. Correct answer is (1) a, d, b, c.