Question

The action of which class of enzyme inhibitors can be reversed by adding an excess of substrate?

• A. Uncompetitive inhibitors
• B. Competitive inhibitors
• C. Non-specific inhibitors
• D. Allosteric inhibitors

Hint:

Competitive inhibitors bind to the active site of enzymes, and their effect can be overcome by increasing the substrate concentration.

Answer 1

The Correct Option is B

Step 1: Understanding the question.
This question asks about the type of enzyme inhibitors whose effect can be reversed by increasing the substrate concentration.
Step 2: Analyzing the options.
- (A) Incorrect, uncompetitive inhibitors bind to the enzyme-substrate complex and cannot be reversed by adding excess substrate.
- (B) Correct, competitive inhibitors compete with the substrate for the active site, and their effects can be overcome by adding an excess of substrate.
- (C) Incorrect, non-specific inhibitors do not specifically interact with the enzyme's active site, and their effects are not reversed by adding substrate.
- (D) Incorrect, allosteric inhibitors bind to a site other than the active site and do not depend on substrate concentration for reversal.
Step 3: Conclusion.
Thus, the correct answer is (B) Competitive inhibitors.