Question

Sorbitol is used in soft gelatin capsules as _______

• A. \( \text{Disintegrating agent} \)
• B. \( \text{Lubricant} \)
• C. \( \text{Thickener} \)
• D. \( \text{Plasticizer} \)

Hint:

Think of "plastic" as flexible – plasticizers make things more flexible. Sorbitol helps the gelatin shell of soft capsules stay flexible.

Answer 1

The Correct Option is D

Sorbitol is a humectant and plasticizer commonly used in the manufacture of soft gelatin capsules. As a plasticizer, it helps to increase the flexibility and reduce the brittleness of the gelatin film, preventing it from becoming too hard and cracking during manufacturing and storage. Its humectant properties also help to maintain the moisture content of the capsule shell, further contributing to its flexibility and integrity. Disintegrating agents are used in solid dosage forms like tablets and hard capsules to promote their breakdown in the gastrointestinal tract. Lubricants are added to tablet and capsule formulations to reduce friction during manufacturing processes. Thickeners are used to increase the viscosity of liquid formulations.