Comprehension

Sixteen patients in a hospital must undergo a blood test for a disease. It is known that exactly one of them has the disease. The hospital has only eight testing kits and has decided to pool blood samples of patients into eight vials for the tests. The patients are numbered 1 through 16, and the vials are labelled A, B, C, D, E, F, G, and H. The following table shows the vials into which each patient’s blood sample is distributed.
PatientVialsPatient Vials
1B,D,F,H9A,D,F,H
2B,D,F,G10A,D,F,G
3B,D,E,H11A,D,E,H
4B,D,E,G12A,D,E,G
5B,C,F,H13A,C,F,H
6B,C,F,G14A,C,F,G
7B,CE,H15A,C,E,H
8B,C,E,G16A,C,E,G
If a patient has the disease, then each vial containing his/her blood sample will test positive. If a vial tests positive, one of the patients whose blood samples were mixed in the vial has the disease. If a vial tests negative, then none of the patients whose blood samples were mixed in the vial has the disease.

Question: 1

Suppose vial C tests positive and vials A, E and H test negative. Which patient has the disease?

Updated On: Aug 20, 2024
  • Patient 14
  • Patient 2
  • Patient 6
  • Patient 8
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The Correct Option is C

Approach Solution - 1

The correct answer is (C): Patient 6

If vial C tests positive vials A , E and H test negative . 

If vial C tests positive following patients can have disease. 

Patient No. 5, 6, 7, 8, 13, 14, 15 & 16

If vials A, E & H test negative 

⇒ following patients can’t have disease

Patients who can’t have disease are :

Patient No. 5, 7, 8, 13, 14, 15 & 16 

⇒ Patient 6 must have disease

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Approach Solution -2

Patients in Vial A: \(9, 10, 11, 12, 13, 14, 15, 16\)
Patients in Vial B: \(1, 2, 3, 4, 5, 6, 7, 8\)
Patients in Vial C: \(5, 6, 7, 8, 13, 14, 15, 16\)
Patients in Vial D: \(1, 2, 3, 4, 9, 10, 11, 12\)
Patients in Vial E: \(3, 4, 7, 8, 11, 12, 15, 16\)
Patients in Vial F: \(1, 2, 5, 6, 9, 10, 13, 14\)
Patients in Vial G: \(2, 4, 6, 8, 10, 12, 14, 16\)
Patients in Vial H: \(1, 3, 5, 7, 9, 11, 13, 15\)

If Vial C tests positive and Vials A, E, and H test negative, then Patient 6 must have the disease, as all other patients in Vial C except Patient 6 are present in at least one of Vials A, E, or H.

So, the correct option is (C): Patient 6.

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Question: 2

Suppose vial A tests positive and vials D and G test negative. Which of the following vials should we test next to identify the patient with the disease?

Updated On: Aug 20, 2024
  • Vial E
  • Vial H
  • Vial C
  • Vial B
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The Correct Option is A

Approach Solution - 1

The correct answer is (A): Vial E

If vial a tests positive, then following patients can have disease. 

Patient No. 9,10,11,12,13,14,15,16 → (1)

Vials D & G test negative

⇒ Following patients, can't have disease patients

No : -1,2,3,4,6,8,9,10,11,12,14,16 → (2)

From both 1 & 2, we ca say that patient No .13 or patient No. 15 can have disease. 

Now we have eliminate or find out who among patient 13 or patient 15 has disease. 

So we should test vials E or F.

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Approach Solution -2

The patients distributed across vials are as follows:
Vial A: \(9, 10, 11, 12, 13, 14, 15, 16\)
Vial B: \(1, 2, 3, 4, 5, 6, 7, 8\)
Vial C: \(5, 6, 7, 8, 13, 14, 15, 16\)
Vial D: \(1, 2, 3, 4, 9, 10, 11, 12\)
Vial E: \(3, 4, 7, 8, 11, 12, 15, 16\)
Vial F: \(1, 2, 5, 6, 9, 10, 13, 14\)
Vial G: \(2, 4, 6, 8, 10, 12, 14, 16\)
Vial H: \(1, 3, 5, 7, 9, 11, 13, 15\)

Given that Vial A tests positive and Vials D and G test negative, the positive patient must be either Patient \(13\) or Patient \(15\).
Neither Patient \(13\) nor Patient \(15\) is present in Vial B, ruling out Option D.
Both patients are present in Vial C, but their disease status cannot be determined regardless of the test result, eliminating Option C.
Similarly, both patients are present in Vial H, but their disease status remains uncertain, dismissing Option B.
Only Patient \(15\) is present in Vial E. If tested positive, Patient \(15\) has the disease; otherwise, it's Patient \(13\).

So, the correct option is (A): Vial E

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Question: 3

Which of the following combinations of test results is NOT possible?

Updated On: Aug 20, 2024
  • Vials A and G positive, vials D and E negative
  • Vials B and D positive, vials F and H negative
  • Vial B positive, vials C, F and H negative
  • Vials A and E positive, vials C and D negative
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The Correct Option is D

Approach Solution - 1

If vials C & D test negative, that means none of the patients through 16 have diseases. But its given in the questions, that exactly one of the patients has disease. This is not possible.

So, the correct answer is (D): Vials A and E positive, vials C and D negative.

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Approach Solution -2

The patients in,
Vial A: \(9, 10, 11, 12, 13, 14, 15, 16\)
Vial B: \(1, 2, 3, 4, 5, 6, 7, 8\)
Vial C: \(5,6,7,8,13,14,15,16\)
Vial D: \(1,2,3,4,9,10,11,12\)
Vial E: \(3,4,7,8,11,12,15,16\)
Vial F: \(1,2,5,6,9,10,13,14\)
Vial G: \(2,4,6,8,10,12,14,16\)
Vial H: \(1,3,5,7,9,11,13,15\)
If vials C and D negative then no patient could test negative.

So, the correct option is (D): Vials A and E positive, vials C and D negative.

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Question: 4

Suppose one of the lab assistants accidentally mixed two patients' blood samples before they were distributed to the vials. Which of the following correctly represents the set of all possible numbers of positive test results out of the eight vials?

Updated On: Aug 20, 2024
  • {4,5}
  • {5,6,7,8}
  • {4,5,6,7,8}
  • {4,5,6,7}
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The Correct Option is C

Approach Solution - 1

i) Let’s assume one of the patients, patient 1 or patient 16 has disease and that patients blood is mixed with other them all 8 vials will test positive. ⇒ 8 has to be one of the answers.

ii) If patient 2 and patients 16’s blood is mixed of one of them has disease then 7 of the 8 vials will test positive. 
So 7 has to be there in the option. 

iii) Let’s assume patient 1 has disease, if his blood is not mixed, then 4 vials will definitely show positive. So 4 also has to be there in answer. 
So the answer must definitely contain 4, 7 and 8.

So, the correct answer is (C): {4,5,6,7,8}

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Approach Solution -2

If either Patient 1 or Patient 16 has the disease and their blood is mixed with others, all 8 vials will test positive, making 8 a necessary option.
When the blood of Patient 2 or Patient 16, one of whom may have the disease, is mixed, 7 out of the 8 vials will test positive, indicating that 7 must be included in the options.
If Patient 1 has the disease and is mixed with Patient 7, then 6 out of the 8 vials will test positive. Similarly, if Patient 1 has the disease and is mixed with Patient 9, then 5 out of the 8 vials will test positive.
Now, assuming Patient 1 has the disease and his blood remains unmixed, 4 vials will definitely show positive results.

Hence, the correct option is (C): {4,5,6,7,8}

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