Question:

Reverse flow of information in central dogma of molecular biology is

Updated On: Aug 15, 2022
  • DNA ? RNA ? Protein
  • DNA.? RNA ? Protein
  • Protein ? DNA ? RNA
  • mRNA ? tRNA ? DNA
Hide Solution
collegedunia
Verified By Collegedunia

The Correct Option is B

Solution and Explanation

Temin and Baltimore (1970) reported that double stranded RNA of Rous Sarcoma Virus (RSV) operates a central dogma reverse (inverse flow of information). RNA of these viruses first synthesises DNA through reverse transcription or teminism. DNA then transfers information to RNA which takes part in translation of coded information to form polypeptide. The mechanism is characteristic of retroviruses, e.g., HIV. Reverse transcription is aided by the enzyme known as reverse transcriptase (RNA dependent DNA polymerase) enzyme.
Was this answer helpful?
0
0

Concepts Used:

The Molecular Basis of Inheritance

DNA Replication:

DNA synthesis is commenced at particular points within the DNA strand referred to as ‘origins’, which are certain coding regions. There are numerous origin sites, and when replication of DNA starts, these sites are mentioned as replication forks. Within the replication, the complex is the enzyme DNA Helicase, so that they can be utilized as a template for replication. DNA Primase is another enzyme that's essential in DNA replication.

RNA:

Ribonucleic acid (RNA) is an essential biological macromolecule that exists all together in biological cells. It is principally involved in the synthesis of proteins, that carry the messenger instructions from DNA, which itself contains the genetic instructions needed for the event and maintenance of life. In some viruses, RNA, in spite of DNA, carries genetic information.

Genetic Code:

Genetic code is the term we use in the manner that the four bases of DNA--the A, C, G, and Ts--are strung together in a way that the ribosome, the cellular machinery, can read them and switch them into a protein. In the ordering, every three nucleotides during a row count as a triplet and code for one amino alkanoic acid.

Read More: Molecular Basis of Inheritance