Question:

Restriction enzymes that recognize the same nucleotide sequence but cleave at different positions are called

Updated On: Nov 18, 2025
  • heterohypekomers
  • isocaudomers
  • isoschizomers
  • neoschizomers
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The Correct Option is D

Solution and Explanation

To answer the question about restriction enzymes, let's explore the relevant concepts:

Restriction enzymes, also known as restriction endonucleases, are proteins that cut DNA at specific sequences. They are essential tools in molecular biology, especially in cloning and analysis of genes. Understanding their classification helps in identifying their specific functions:

  • Isoschizomers: These enzymes recognize and cleave the same DNA sequence at the same site.
  • Neoschizomers: Although they recognize the same nucleotide sequence as isoschizomers, neoschizomers cleave DNA at different positions from their isoschizomers. This characteristic differentiates neoschizomers from isoschizomers.
  • Isocaudomers: Enzymes that generate compatible cohesive ends but recognize slightly different sequences.
  • Heterohypekomers: This term is not commonly recognized in the context of restriction enzymes.

Given the definitions, the correct answer is neoschizomers because they are enzymes that recognize the same nucleotide sequence but cleave at different positions when compared to their isoschizomers.

Therefore, the concept and distinguishing feature of neoschizomers fits the description in the question, leading to the correct answer choice.

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