Question

Resolution of HPLC can not be modified by ________.

• A. decreasing particle size
• B. decreasing column diameter
• C. changing flow rate
• D. changing detector

Hint:

Remember: Resolution in HPLC is about separation, not detection.

Answer 1

The Correct Option is D

HPLC resolution is primarily affected by factors such as particle size, flow rate, and column dimensions. The detector type does not influence the chromatographic separation or resolution but only affects detection sensitivity.