In the first blank, we need an interrogative adjective because it is followed directly by a noun (“programme”). 
Quel (which/what) is the appropriate form that agrees in gender and number with “programme” (masculine singular). 
So: Quel programme a du contenu intéressant ? (Which program has interesting content?) 
In the second blank, there is no noun following — only the verb “est.” This signals that we need a pronoun, not an adjective. 
“Lequel” is an interrogative pronoun that replaces a previously mentioned noun and agrees in gender and number. 
Here, it replaces “programme” again. 
So: Lequel est banal ? (Which one is boring?) 
Final sentence: Quel programme a du contenu intéressant et lequel est banal ?