Question

Prerequisite for sympathetic ophthalmitis

• A. Penetrating injury to the eye
• B. Blunt ocular tumor
• C. Chemical injury
• D. Urinary tract infection

Answer 1

The Correct Option is A

Sympathetic ophthalmitis is a rare, bilateral granulomatous uveitis that occurs after a penetrating injury to one eye. This condition is the result of an autoimmune response, where the immune system mistakenly attacks the uninjured eye in reaction to the antigen released from the injured eye. Understanding the mechanism can help prevent and manage this condition:

1. Prerequisite Condition: The primary prerequisite for sympathetic ophthalmitis is a penetrating injury to one eye. This can lead to exposure and release of ocular antigens which are typically secluded within the eye, causing an autoimmune response.
2. Comparison of Options:

   Condition	Relation to Sympathetic Ophthalmitis
   Penetrating injury to the eye	Can lead to sympathetic ophthalmitis due to exposure to ocular antigens
   Blunt ocular tumor	No direct correlation with sympathetic ophthalmitis
   Chemical injury	Does not typically cause sympathetic ophthalmitis
   Urinary tract infection	Unrelated to sympathetic ophthalmitis

3. Conclusion: The correct option is a penetrating injury to the eye as it directly relates to the development of sympathetic ophthalmitis.