Identifying excipients for formulation development with enhanced bioavailability
Monitoring plasma levels of drugs for better pharmacodynamics
Predicting half-life of drugs
Creating a 3D model of the necessary features to interact with a target
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Solution and Explanation
Pharmacophore modelling is a computational approach used in drug design to identify the spatial arrangement of features in a molecule that are necessary to ensure optimal interactions with a specific biological target. It helps in virtual screening and lead optimization.