Question

Pegloticase is used for the treatment of an Ankylosing spondylosis

• A. Reactive Arthritis
• B. CPPD
• C. Chronic tophaceous gout
• D. Refractory Rheumatoid arthritis

Answer 1

The Correct Option is C

Pegloticase is a medication that is primarily used for the treatment of chronic gout, specifically chronic tophaceous gout. This condition is characterized by the accumulation of uric acid crystals in the joints, leading to inflammation and pain. Pegloticase functions by breaking down uric acid into a more soluble compound, thereby reducing the uric acid levels in the body and preventing the formation of gouty tophi.

Given the options:

Reactive Arthritis

CPPD

Chronic tophaceous gout

Refractory Rheumatoid arthritis

The correct answer is Chronic tophaceous gout. This is because Pegloticase is specifically indicated for cases where gout has become severe and chronic, addressing high uric acid levels.